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‘Inflammation Clock’ Can Reveal Body’s Biological Age

14 November 2021

Using machine learning, researchers created a tool that might help doctors improve people’s healthy lifespan


A new type of age ‘clock’ can assess chronic inflammation to predict whether someone is at risk of developing age-related disorders such as cardiovascular and neurodegenerative disease. The clock measures ‘biological age’, which takes health into consideration and can be higher or lower than a person’s chronological age.


The inflammatory ageing clock (iAge), reported on 12 July in Nature Aging, is one of the first tools of its kind to use inflammation to assess health. Other age clocks have used epigenetic markers, chemical groups that tag a person’s DNA as they age and are passed along as cells divide. The researchers who developed iAge hope that, because inflammation is treatable, the tool could help doctors determine who would benefit from intervention—potentially extending the number of years a person lives in good health.


Scientific American